Advanced Radiostereometric Analysis (RSA) Demonstrates Exceptional Implant-Bone Fixation and Low Wear Rates, Potentially Setting New Standards for Hip Replacement Longevity

Demonstrated Femoral subsidence measurements obtained were significantly under published safety thresholds

Minimal polyethylene linear wear reported over the five-year wear study period

BOCA RATON, Fla., Sept. 23, 2025 /PRNewswire/ -- Hip Innovation Technology, LLC, a late-stage medical device company delivering innovative orthopedic device solutions to advance the quality of life and quality of care for patients, today announced that Thomas Turgeon, MD, Associate Professor, Max Rady College of Medicine, presented updated data from the company's study assessing its unique Reverse Hip Replacement System's (Reverse HRS) stability and wear rates with up to 5 years of patient follow-up employing radiostereometric analysis. The data was presented during a plenary session at the 2025 International Society for Technology in Arthroplasty (ISTA) in Rome, Italy.

The novel Reverse HRS design reverses traditional hip replacement architecture by utilizing a femoral cup and acetabular ball configuration, providing enhanced mechanical stability at extremes of motion. This unique and potentially groundbreaking approach addresses critical limitations of conventional hip replacements, particularly for patients with complex anatomical challenges.

"This landmark five-year radiostereometric analysis (RSA) study has demonstrated exceptional implant-bone fixation stability and remarkably low wear rates for a revolutionary reverse total hip arthroplasty (RTHA) design, potentially transforming treatment outcomes for patients with severe hip osteoarthritis," said Thomas Turgeon, MD. "The comprehensive study, involving 22 patients at a single investigational center, represents one of the most rigorous long-term assessments of this innovative hip replacement technology to date."

Distinctive Design Delivers Exceptional Stability
The study's findings show femoral subsidence measurements consistently below 0.06mm and acetabular subsidence below 0.09mm at the five-year mark; significantly under published safety thresholds of 1.5mm and 1mm respectively. These results indicate exceptional implant-bone integration and suggest a reduced risk of long-term aseptic loosening, a primary concern in hip replacement surgery.

"Further, we are very excited that these preliminary data with no screws in the acetabular cup are equal to the 2-year data with screws in the acetabular cup," said Dr. Turgeon. "The benefits of cementless screwless implants include reduced osteolysis, faster surgical time, fewer complications and more natural load transfer."

Clinical Excellence Meets Patient Outcomes
Perhaps most significantly for patients, polyethylene linear wear measurements remained at the detection limit throughout the study period, with five-year wear rates of just 0.19±0.16mm. This minimal wear profile, combined with improvements in patient-reported outcome measures (PROMs) for both function and pain, demonstrates the system's dual success in mechanical performance and quality of life enhancement.

"We believe that these five-year RSA results represent a watershed moment for hip replacement technology," said George Diamantoni, Chief Executive Officer, Hip Innovation Technology. "The combination of exceptional fixation stability and minimal wear rates provides compelling evidence that this reverse design philosophy can deliver the long-term durability and clinical outcomes that both surgeons and patients demand."

Addressing Critical Healthcare Needs
With hip replacement procedures projected to increase dramatically due to aging populations, the mid-term stability of this Reverse HRS design addresses a critical healthcare challenge. The technology's enhanced stability at motion extremes makes it particularly valuable for younger, more active patients who traditionally face higher revision risks with conventional implants.

The study cohort, consisting of 11 females and 11 males with a mean age of 70.8 years, represents typical hip replacement demographics while demonstrating outcomes that exceed traditional performance benchmarks across all measured parameters.

About the Reverse HRS
The Reverse HRS is a Metal-on-Polyethylene reverse geometry hip prosthesis designed to improve stability at extended ranges of motion and reduce the risk of dislocation. Like most conventional systems, the Reverse HRS consists of a femoral stem, an acetabular cup and a cobalt-chrome ball that articulates within a polyethylene liner. Unlike existing total hip replacement systems, the ball is placed on a trunnion within the acetabular cup instead of the femoral stem, and the polyethylene liner is attached to a femoral cup, which then attaches to the femoral stem, as opposed to the polyethylene liner being attached to the acetabular cup.

About Hip Innovation Technology, LLC
Hip Innovation Technology, founded in 2011, develops innovative orthopedic device solutions designed to advance quality of life and quality of care for patients. In partnership with healthcare professionals worldwide, our goal is to design, manufacture and ultimately market innovative orthopedic reconstructive and related surgical product solutions in areas of high unmet medical need.

For more information, visit www.hipinnovationtechnology.com.

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SOURCE Hip Innovation Technology, LLC