Springs Rejuvenation Brings Minimally Invasive Stem Cell Exosome Therapy to 5 US Clinics
Aventura, United States - September 15, 2026 / Springs Rejuvenation /
Springs Rejuvenation has expanded its physician-supervised stem cell and exosome joint therapy program to all five of its U.S. clinic locations -- New York City, Los Angeles, Austin, Miami, and Atlanta -- making its minimally invasive joint restoration protocol more broadly accessible to patients experiencing knee discomfort, hip stiffness, shoulder issues, and back pain.
The Stem 3 Protocol: A Structured Approach to Joint Wellness
At the core of the Springs Rejuvenation offering is the Stem 3 Protocol, a multi-step procedure that pairs stem cells with exosomes to address joint concerns in a structured, physician-supervised setting. The protocol is designed to help support joint comfort and mobility, and is administered by licensed medical professionals at each of the five clinic locations across the United States.
The procedure utilizes a 0.9mm micro FUE procedure methodology, a technique typically associated with minimally invasive hair restoration but applied here within a broader regenerative framework. By incorporating exosomes alongside stem cells, the protocol targets the cellular environment around affected joints in a manner that may help support the body's natural processes.
Dr. Charles Pereyra, MD, who oversees the clinical program at Springs Rejuvenation, has noted observations consistent with patient-reported improvements in comfort and range of motion. "In our clinical experience, patients dealing with knee and hip concerns have reported that the stem cell and exosome protocol may help support their mobility over time -- though individual responses vary, and we approach each case with that in mind," said Dr. Charles Pereyra, MD of Springs Rejuvenation.
Stem Cells and Exosomes: The Biological Basis
Research published in the Journal of Translational Medicine (2021) suggested that exosome-based approaches may help support tissue repair and reduce inflammatory signals in joint environments, though findings remain preliminary and results are not guaranteed. Springs Rejuvenation draws on this body of emerging science to inform its protocol design, while maintaining that all procedures are administered under physician supervision and that outcomes may vary by patient.
The clinic's use of a minimally invasive hair restoration-derived micro FUE methodology -- adapted within the broader regenerative context -- reflects the clinic's approach to precision and reduced procedural burden. The combination of stem cells with exosomes is central to the Springs Rejuvenation formula, and is produced in an FDA-approved laboratory.
Five-Location Availability Across the United States
With clinics now operating in New York City, Los Angeles, Austin, Miami, and Atlanta, Springs Rejuvenation offers patients in major U.S. markets access to its joint wellness program without the need to travel to a single specialized center. Each location maintains physician-supervised care, consistent with the clinical standards established under Dr. Pereyra's oversight.
Patients dealing with back pain, hip stiffness, shoulder concerns, or knee discomfort may be candidates for the stem cell and exosome protocol, though suitability is determined on an individual basis following consultation with a qualified medical professional at the clinic.
The program positions Springs Rejuvenation as a minimally invasive alternative for individuals seeking joint comfort and mobility support outside of surgical intervention. The availability of the protocol across all five clinic sites means that physician-supervised care using the Stem 3 Protocol is accessible to a wider patient population spanning both coasts and the U.S. South.
Separately, Springs Rejuvenation also offers advanced FUE hair transplant procedures and stem cell exosome therapy for hair-related concerns, with the micro FUE procedure available at its clinic network for patients seeking minimally invasive hair restoration options.
About Springs Rejuvenation
Springs Rejuvenation is a physician-supervised regenerative wellness clinic network operating five locations across the United States, including New York City, Los Angeles, Austin, Miami, and Atlanta. The practice offers stem cell and exosome protocols for joint wellness and hair restoration under medical supervision, including the Stem 3 Protocol and micro FUE procedure.
---
Our Stem Cell exosome formula is produced in an FDA approved lab, but is not an FDA approved therapy. It is currently in the experimental stages -- all information provided is based on our experience with patients. Results may vary. Consult with a qualified medical professional.
Learn more at Springs Rejuvenation
Contact Information:
Springs Rejuvenation
245 5th Ave 3rd Floor Suite 307
Aventura, Florida 10016
United States
Charles Pereyra
(305) 363-0718
https://home.springsrejuvenation.com
